Arcade operators implement rigorous cleaning and sanitation protocols to ensure player safety and maintain equipment longevity. Daily cleaning routines involve wiping down high-contact surfaces like control panels, joysticks, trackballs, and buttons with approved disinfectant solutions that won't damage sensitive components. Many operators use alcohol-based cleaners or EPA-registered disinfectants that effectively eliminate germs without harming electronic parts.

Weekly deep cleaning procedures include more comprehensive maintenance where operators might remove control panels to clean underneath buttons and joysticks. Special attention is given to ticket and token slots, which can accumulate debris. Some facilities employ UV-C light sterilization systems for added protection against pathogens, particularly following pandemic-era health concerns.

Professional arcade operators follow manufacturer guidelines for cleaning specific components, using appropriate tools like microfiber cloths, compressed air for dust removal, and specialized cleaning solutions for screens and displays. Many establish cleaning logs to track maintenance schedules and ensure consistency across their facility. The industry has developed enhanced sanitation standards, with many operators implementing visible "recently cleaned" indicators to reassure customers.

Proper sanitation not only addresses health concerns but also preserves machine functionality by preventing sticky buttons and malfunctioning controls caused by dirt buildup. Operators balance effective cleaning with equipment preservation, ensuring both player safety and optimal gaming performance through disciplined maintenance practices.