Designing an arcade machine for players with mobility issues requires thoughtful consideration to ensure inclusivity and accessibility. Key factors include adjustable height and seating options to accommodate wheelchairs, large and easy-to-press buttons for limited dexterity, and customizable control layouts. Tactile feedback and audio cues can enhance the experience for players with visual or auditory impairments. Additionally, incorporating joysticks with varying resistance levels and touchscreen interfaces can cater to diverse needs. Ensuring the machine is stable and has ample space around it for maneuverability is also crucial. By prioritizing these elements, designers can create arcade machines that are enjoyable and accessible for all players.